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5-Nitrobenzimidazole

5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia[1][2].

Product Specifications

CAS Number

94-52-0

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative; Xanthine Oxidase

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/5-nitrobenzimidazole.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=[N+]([O-])C1=CC2=C(N=CN2)C=C1

Molecular Formula

C7H5N3O2

Molecular Weight

163.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Hsieh JF, et al. The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. Bioorg Med Chem. 2007 May 15;15 (10) :3450-6. |[2]Deýlová D, et al. Voltammetric Determination of 4‐Nitrophenol and 5‐Nitrobenzimidazole Using Different Types of Silver Solid Amalgam Electrodes–A Comparative Study. Electroanalysis, 2011, 23 (7) : 1548-1555.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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