5-Nitrobenzimidazole
5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia[1][2].
Product Specifications
CAS Number
94-52-0
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative; Xanthine Oxidase
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-nitrobenzimidazole.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[N+]([O-])C1=CC2=C(N=CN2)C=C1
Molecular Formula
C7H5N3O2
Molecular Weight
163.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Hsieh JF, et al. The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. Bioorg Med Chem. 2007 May 15;15 (10) :3450-6. |[2]Deýlová D, et al. Voltammetric Determination of 4‐Nitrophenol and 5‐Nitrobenzimidazole Using Different Types of Silver Solid Amalgam Electrodes–A Comparative Study. Electroanalysis, 2011, 23 (7) : 1548-1555.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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