5-Nitrobenzimidazole
5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia[1][2].
Product Specifications
CAS Number
94-52-0
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative; Xanthine Oxidase
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-nitrobenzimidazole.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[N+]([O-])C1=CC2=C(N=CN2)C=C1
Molecular Formula
C7H5N3O2
Molecular Weight
163.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Hsieh JF, et al. The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. Bioorg Med Chem. 2007 May 15;15 (10) :3450-6. |[2]Deýlová D, et al. Voltammetric Determination of 4‐Nitrophenol and 5‐Nitrobenzimidazole Using Different Types of Silver Solid Amalgam Electrodes–A Comparative Study. Electroanalysis, 2011, 23 (7) : 1548-1555.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HP232065 200 Reactions
Nesprin 2 (SYNE2) Human qPCR Primer Pair (NM_182914)
Sign In for Pricing
View Details 
LY433412 100 µg
SLC44A4 (NM_001178044) Human Over-expression Lysate
Sign In for Pricing
View Details 