Oil Red O

Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses[1].

Product Specifications

CAS Number

[1320-06-5]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/oil-red-o.html

Purity

95.0

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=CC=C2C=CC=CC2=C1/N=N/C3=CC(C)=C(/N=N/C4=CC(C)=CC=C4C)C=C3C

Molecular Formula

C26H24N4O

Molecular Weight

408.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Mehlem A, et al. Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease. Nat Protoc. 2013 Jun;8 (6) :1149-54.|[2]Escorcia W, et al. Quantification of Lipid Abundance and Evaluation of Lipid Distribution in Caenorhabditis elegans by Nile Red and Oil Red O Staining. J Vis Exp. 2018 Mar 5; (133) :57352.