Rabbit anti Human SALL4
Product Specifications
Background
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.
CAS Number
9007-83-4
Synonyms
Sal-like Protein 4, Zinc finger Protein 797, Zinc finger Protein SALL4
UniProt
Q9UJQ4
Host
Rabbit
Species Reactivity
Human
Isotype
Ig
Conjugation
Affinity Purified
Type
Antigen Immunoaffinity Purified Polyclonal
Applications
WB, IHC
Purification Method
Antigen Immunoaffiinity Purification
Assay Principle
Antibody can be used for Immunohistochemistry (2-4 µg/mL) and Western blotting (1-2 µg/mL). Optimal concentration should be evaluated by serial dilutions.
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline with 0,08% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
References & Citations
1. Ma, Y., et al. ‘SALL4, a novel oncogene, is constitutively expressed in Human acute myeloid leukemia (AML) and induces AML in transgenic mice.’ Blood, 108, 2726-2735 (2006)
2. Kohlhase, J., et al. ‘Okihiro syndrome is caused by SALL4 mutations.’ Hum. Mol. Genet., 11, 2979-2987 (2002)
3. Yang, F., et al. ‘Sumoylation is important for stability, subcellular localization, and transcriptional activity of SALL4, an essential stem cell transcription factor.’ J. Biol. Chem., 287, 38600-38608 (2012)
Shipping Conditions
Ambient Temperature, freeze upon arrival
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
WB
Frequently Asked Questions
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