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Rabbit anti Human SALL4

Product Specifications

Background

Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.

CAS Number

9007-83-4

Synonyms

Sal-like Protein 4, Zinc finger Protein 797, Zinc finger Protein SALL4

UniProt

Q9UJQ4

Host

Rabbit

Species Reactivity

Human

Isotype

Ig

Conjugation

Affinity Purified

Type

Antigen Immunoaffinity Purified Polyclonal

Applications

WB, IHC

Purification Method

Antigen Immunoaffiinity Purification

Assay Principle

Antibody can be used for Immunohistochemistry (2-4 µg/mL) and Western blotting (1-2 µg/mL). Optimal concentration should be evaluated by serial dilutions.

Stability

See expiration date on vial

Concentration

See vial for Concentration

Form

Provided as solution in phosphate buffered saline with 0,08% sodium azide

Precautions

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

References & Citations

1. Ma, Y., et al. ‘SALL4, a novel oncogene, is constitutively expressed in Human acute myeloid leukemia (AML) and induces AML in transgenic mice.’ Blood, 108, 2726-2735 (2006) 2. Kohlhase, J., et al. ‘Okihiro syndrome is caused by SALL4 mutations.’ Hum. Mol. Genet., 11, 2979-2987 (2002) 3. Yang, F., et al. ‘Sumoylation is important for stability, subcellular localization, and transcriptional activity of SALL4, an essential stem cell transcription factor.’ J. Biol. Chem., 287, 38600-38608 (2012)

Shipping Conditions

Ambient Temperature, freeze upon arrival

Storage Conditions

Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles

Functional Analysis

WB

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