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(+) -SJ733

(+) -SJ733 is an anti-malaria agent which can also inhibit Na+-ATPase PfATP4.

Product Specifications

CAS Number

[1424799-20-1]

Product Name Alternative

SJ000557733

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335, H412

Target

Na+/K+ ATPase; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/__addition__-SJ733.html

Purity

99.79

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C([C@@H](C1=C2C=CC=C1)[C@@H](C3=CC=CN=C3)N(CC(F)(F)F)C2=O)NC4=CC=C(F)C(C#N)=C4

Molecular Formula

C24H16F4N4O2

Molecular Weight

468.40

Precautions

H302, H315, H319, H335, H412

References & Citations

[1]Jimenez-Diaz MB, et al. (+) -SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci U S A. 2014 Dec 16;111 (50) :E5455-62.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19556/plus-SJ733-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19556/plus-SJ733-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 1

Isoform

Plasmodium

Available Sizes

Curated Selection

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