(+)-SJ733
Product Specifications
UNSPSC Description
(+)-SJ733 is an anti-malaria agent which can also inhibit Na+-ATPase PfATP4.
Target Antigen
Na+/K+ ATPase; Parasite
Type
Reference compound
Related Pathways
Anti-infection;Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/__addition__-SJ733.html
Purity
99.45
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](C1=C2C=CC=C1)[C@@H](C3=CC=CN=C3)N(CC(F)(F)F)C2=O)NC4=CC=C(F)C(C#N)=C4
Molecular Weight
468.40
References & Citations
[1]Jimenez-Diaz MB, et al. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5455-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19556/plus-SJ733-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19556/plus-SJ733-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
1424799-20-1
Available Sizes
Curated Selection
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