What is the catalog number for Ganomycin I?

The catalog number for Ganomycin I is HY-N10076.

What sizes are available for Ganomycin I?

Ganomycin I is available in the following size(s): 1 Each.

Is Ganomycin I in stock?

Ganomycin I is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ganomycin I?

Ganomycin I is manufactured by QuantiMol.

What is the estimated delivery time for Ganomycin I?

Estimated delivery time for Ganomycin I is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ganomycin I?

The safety data sheet for Ganomycin I is available here: http://file.medchemexpress.com/batch_PDF/HY-N10076/.

Ganomycin I

Ganomycin I is a dual inhibitor of α-Glucosidase and HMG-CoA reductase. Ganomycin I can also inhibits HIV protease. Ganomycin I exhibits anti-diabetic and anti-osteoclastogenesis effects[1][2].

Product Specifications

CAS Number

1191255-15-8

UNSPSC

12352005

Target

Glycosidase; HIV Protease; HMG-CoA Reductase (HMGCR)

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ganomycin-i.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C=C(C=C1)O)[C@@]2([H])C=C(C(O2)=O)CC/C=C(C)/CC/C=C(C)/C

Molecular Formula

C21H26O4

Molecular Weight

342.43

References & Citations

[1]Tran PT, et, al. Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1. Phytomedicine. 2019 Mar 1;55:1-8.|[2]Wang K, et, al. Structural Modification of Natural Product Ganomycin I Leading to Discovery of a α-Glucosidase and HMG-CoA Reductase Dual Inhibitor Improving Obesity and Metabolic Dysfunction in Vivo. J Med Chem. 2018 Apr 26;61 (8) :3609-3625.