RET-IN-28

RET-IN-28 (Compound 16) is a RET (transmembrane receptor tyrosine protein kinase) inhibitor. RET-IN-28 inhibits the activity of the mutant RET enzyme (RET-V804M), and can be applied to cancer research[1].

Product Specifications

CAS Number

[2479961-45-8]

UNSPSC

12352005

Target

RET

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ret-in-28.html

Smiles

CC(C=C1)=NC=C1CN(C(C2)C3)C2CN3C4=NC=C(C5=NC(NC6=NNC(C)=C6)=CC(C)=N5)C=C4

Molecular Formula

C26H29N9

Molecular Weight

467.57

References & Citations

[1]Chen Z, et al. Heterocyclic compound, pharmaceutical composition comprising same, preparation method therefor, and use thereof. World Intellectual Property Organization, WO2020168939A1. 2020-08-27.