RET-IN-28
RET-IN-28 (Compound 16) is a RET (transmembrane receptor tyrosine protein kinase) inhibitor. RET-IN-28 inhibits the activity of the mutant RET enzyme (RET-V804M), and can be applied to cancer research[1].
Product Specifications
CAS Number
[2479961-45-8]
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ret-in-28.html
Smiles
CC(C=C1)=NC=C1CN(C(C2)C3)C2CN3C4=NC=C(C5=NC(NC6=NNC(C)=C6)=CC(C)=N5)C=C4
Molecular Formula
C26H29N9
Molecular Weight
467.57
References & Citations
[1]Chen Z, et al. Heterocyclic compound, pharmaceutical composition comprising same, preparation method therefor, and use thereof. World Intellectual Property Organization, WO2020168939A1. 2020-08-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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