Isonicotinic acid
Isonicotinic acid is an Isoniazid metabolite. The Isonicotinic acid derivative Enisamium inhibits the replication of multiple subtypes of influenza A virus[1][2].
Product Specifications
CAS Number
55-22-1
UNSPSC
12352005
Hazard Statement
H319
Target
Drug Intermediate; Drug Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/isonicotinic-acid.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC=NC=C1
Molecular Formula
C6H5NO2
Molecular Weight
123.11
Precautions
H319
References & Citations
[1]Seng KY, et al. Population pharmacokinetic analysis of isoniazid, acetylisoniazid, and isonicotinic acid in healthy volunteers. Antimicrob Agents Chemother. 2015 Nov;59 (11) :6791-9.|[2]Boltz D, et al. Activity of enisamium, an isonicotinic acid derivative, against influenza viruses in differentiated normal human bronchial epithelial cells. Antivir Chem Chemother. 2018 Jan-Dec;26:2040206618811416.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
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