Chromogenic Substrate for Thrombin

<strong>Chromogenic Substrate for Thrombin</strong>_x000D_ <strong>Catalog number:</strong> B2014469_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 625.6_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Chromogenic Substrate for Thrombin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Meddahi S, Bara L, Fessi H, Samama MM. Standard measurement of clot-bound thrombin by using a chromogenic substrate for thrombin Thromb Res. 2004;114(1):51-6._x000D_ 2: Zhao Q, Wang X. An aptamer-capture based chromogenic assay for thrombin Biosens Bioelectron. 2012 Apr 15;34(1):232-7._x000D_ 3: Yamaguchi T, Shinozawa K, Nagatoishi S, Mitsuhashi A, Bingo M, Inaba H, Amano K, Tsumoto K, Kinai E. In vitro validation of chromogenic substrate assay for evaluation of surrogate FVIII-activity of emicizumab Thromb Res. 2023 Feb;222:131-139._x000D_ 4: Arian D, Harenberg J, Krämer R. A Chromogenic and Fluorogenic Peptide Substrate for the Highly Sensitive Detection of Proteases in Biological Matrices J Med Chem. 2016 Aug 25;59(16):7576-83._x000D_ 5: Aiyappa PA. Chromogenic substrate spectrophotometric assays for the measurement of clotting function Ann N Y Acad Sci. 1981;370:812-21._x000D_ 6: Wang C, Zhao Q. A competitive thrombin-linked aptamer assay for small molecule: aflatoxin B(1) Anal Bioanal Chem. 2019 Oct;411(25):6637-6644._x000D_ 7: Jaffer IH, Chan N, Roberts R, Fredenburgh JC, Eikelboom JW, Weitz JI. Comparison of the ecarin chromogenic assay and diluted thrombin time for quantification of dabigatran concentrations J Thromb Haemost. 2017 Dec;15(12):2377-2387._x000D_ 8: Hafner G, Roser M, Nauck M. Methods for the monitoring of direct thrombin inhibitors Semin Thromb Hemost. 2002 Oct;28(5):425-30._x000D_ 9: Blombäck M, Blombäck B, Olsson P, Svendsen L. The assay of antithrombin using a synthetic chromogenic substrate for thrombin Thromb Res. 1974 Nov;5(5):621-32._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/3937277">10: Rosén S, Andersson M, Blombäck M, Hägglund U, Larrieu MJ, Wolf M, Boyer C, Rothschild C, Nilsson IM, Sjörin E, et al. Clinical application of a chromogenic substrate method for determination of factor VIII activity Thromb Haemost. 1985 Dec 17;54(4):818-23.</a>_x000D_ _x000D_ <strong>Products Related to Chromogenic Substrate for Thrombin can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>