BET bromodomain inhibitor
BET bromodomain inhibitor is an orally active BET inhibitor with an IC50 of 14 nM against BRD4 (1) . BET bromodomain inhibitor can inhibit the proliferation of tumor cells and induce cell cycle arrest and apoptosis. BET bromodomain inhibitor can be used in the research of tumors[1][2].
Product Specifications
CAS Number
1505453-59-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BET_bromodomain_inhibitor.html
Purity
99.53
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N)C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=CC(C4=CN(C)N=C4)=CC=C3C5=C1ON=C5C
Molecular Formula
C24H20ClN5O2
Molecular Weight
445.90
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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