CST3 Polyclonal Antibody
Product Specifications
Background
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.
Abbreviation
CST3
UniProt
P01034
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human CST3 protein expressed by E.coli
Target
AD8; Amyloid angiopathy and cerebral hemorrhage; ARMD11; CST3 protein; Cystatin 3; CystatinC; Epididymis secretory protein Li 2; bA218C14.4; Gamma trace; HCCAA; HEL S 2; Neuroendocrine basic polypeptide; Post gamma globulin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Tags and Cell markers; Cell Biology; Stem Cells; Cardiovascular
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:250-1:500
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa
Observed Molecular Weight
15 kDa
Isotype
IgG
Available Sizes
Documents
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