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CST3 Polyclonal Antibody

Product Specifications

Background

Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.

Abbreviation

CST3

UniProt

P01034

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human CST3 protein expressed by E.coli

Target

AD8; Amyloid angiopathy and cerebral hemorrhage; ARMD11; CST3 protein; Cystatin 3; CystatinC; Epididymis secretory protein Li 2; bA218C14.4; Gamma trace; HCCAA; HEL S 2; Neuroendocrine basic polypeptide; Post gamma globulin

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Tags and Cell markers; Cell Biology; Stem Cells; Cardiovascular

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:250-1:500

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/stqapo

Product MSDS

https://789.bio/eb/1h5RKG

Calculated Molecular Weight

15 kDa

Observed Molecular Weight

15 kDa

Isotype

IgG

Available Sizes

Curated Selection

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