Anti-ATR Antibody

Rabbit Polyclonal Antibody specific to ATR

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

EC 2.7.11.1, Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1

Gene Name

ATR

NCBI Gene ID

UniProt

Q13535

Accession Number

NP_001175

Cellular Locus

Nucleus, Chromosome

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthetic peptide representing a portion of the protein encoded within exon 29 (LocusLink ID 545).

Target Antigen

Serine/threonine-protein kinase ATR

Target

ATR

Clonality

Polyclonal

Isotype

Whole IgG

Type

Antibody

Applications

WB, IP

Field of Research

Enzymes

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium which is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Tris

Function

Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. RUniProtKB:Q9JKK8, PubMed:10597277, PubMed:10608806, PubMed:10859164, PubMed:11114888, PubMed:11418864, PubMed:11673449, PubMed:11721054, PubMed:11865061, PubMed:12526805, PubMed:12791985, PubMed:12814551, PubMed:14657349, PubMed:14729973, PubMed:14742437, PubMed:15210935, PubMed:15314022, PubMed:15496423, PubMed:16260606, PubMed:21144835, PubMed:27723717, PubMed:27723720, PubMed:33848395, PubMed:9427750, PubMed:9636169, PubMed:9925639}.