Valnoctamide

Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors[1].

Product Specifications

CAS Number

[4171-13-5]

Product Name Alternative

Valmethamide

UNSPSC

12352211

Hazard Statement

H302

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/valnoctamide.html

Concentration

10mM

Purity

99.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CCC(C(C(N)=O)CC)C

Molecular Formula

C8H17NO

Molecular Weight

143.23

Precautions

H302

References & Citations

[1]Spampanato J, et al. Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus. Epilepsia. 2014 Sep;55 (9) :e94-8.