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FN1 Polyclonal Antibody

Product Specifications

Background

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity) . Participates in the regulation of type I collagen deposition by osteoblasts (By similarity) . Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation

Abbreviation

FN1

UniProt

P02751

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human FN1 protein expressed by E.coli

Target

DKFZp686F; DKFZp686H; DKFZp686I; DKFZp686O; FN1; CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; fibronectin; Cold insoluble globulin; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED B; Fibronectin 1; Migration stimulating factor; Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; Cold-insoluble globulin; fFN

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cardiovascular; Signal Transduction; Stem Cells; Cancer; Developmental Biology

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:250-1:500

Buffer

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

272 kDa

Observed Molecular Weight

260-300 kDa

Isotype

IgG

Available Sizes

Curated Selection

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