FN1 Polyclonal Antibody
Product Specifications
Background
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity) . Participates in the regulation of type I collagen deposition by osteoblasts (By similarity) . Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation
Abbreviation
FN1
UniProt
P02751
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human FN1 protein expressed by E.coli
Target
DKFZp686F; DKFZp686H; DKFZp686I; DKFZp686O; FN1; CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; fibronectin; Cold insoluble globulin; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED B; Fibronectin 1; Migration stimulating factor; Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; Cold-insoluble globulin; fFN
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cardiovascular; Signal Transduction; Stem Cells; Cancer; Developmental Biology
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:250-1:500
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
272 kDa
Observed Molecular Weight
260-300 kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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