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(Met (O) 27) -Glucagon (1-29) (human, rat, porcine)

Selected Variant

HY-P4672

Size: 1 Each

(Met (O) 27) -Glucagon (1-29) (human, rat, porcine) is a modified glucagon. (Met (O) 27) -Glucagon (1-29) (human, rat, porcine) has the same maximum glucose-synthesizing activity in rat hepatocytes as native glucagon, but it is less potent, suggesting a crucial role of methionine in the binding of glucagon to its hepatic receptor[1].

Product Specifications

CAS Number

75217-63-9

UNSPSC

12352209

Target

GCGR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/met-o-27-glucagon-1-29-human-rat-porcine.html

Solubility

H2O

Smiles

[HSQGTFTSDYSKYLDSRRAQDFVQWL-{Met(O)}-NT]

Molecular Formula

C153H225N43O50S

Molecular Weight

3498.75

References & Citations

[1]Nooijen WJ, et al. Immunogenicity and bioactivity of glucagon, modified at methionine-27. Horm Metab Res. 1979 Aug;11 (8) :459-63.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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