[Arg-15,20,21, Leu17]-PACAP-Gly-Lys-Arg-NH2

[Arg-15, -20, -21, Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect[1].

Product Specifications

CAS Number

[176785-25-4]

Product Name Alternative

BM-PACAP

UNSPSC

12352209

Target

PACAP Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/arg-15-20-21-leu17-pacap-gly-lys-arg-nh2.html

Solubility

H2O

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H]([C@@H](C)CC)NC(CNC([C@H](CC(O)=O)NC([C@H](CO)NC([C@@H](N)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC=C(C=C5)O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C157H253N53O42

Molecular Weight

3555.02

References & Citations

[1]Yoshihara S, et al. Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi. Regul Pept. 2004 Dec 15;123 (1-3) :161-5.|[2]Yoshihara S, et al. Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro. Br J Pharmacol. 1997 Aug;121 (8) :1730-4.