Antifungal agent 92
Antifungal agent 92 (Compound 21) is a potent antifungal agent with an EC50 of 4.4 μM against Sclerotinia sclerotiorum. Antifungal agent 92 can induce abnormal mitochondrial morphology, loss of mitochondrial membrane potential, and reactive oxygen species (ROS) accumulation in Sclerotinia sclerotiorum. Antifungal agent 92 is a moderate promiscuous inhibitor of mitochondrial complexes II and III[1].
Product Specifications
CAS Number
3020687-94-6
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-92.html
Solubility
10 mM in DMSO
Smiles
O=C1OC(C)=CC(O)=C1C(CCC2CCCC2)=O
Molecular Formula
C14H18O4
Molecular Weight
250.29
References & Citations
[1]Wang D, et al. Chelation of the Optimal Antifungal Pogostone Analogue with Copper (II) to Explore the Dual Antifungal and Antibacterial Agent. J Agric Food Chem. 2024 Feb 28;72 (8) :3894-3903.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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