Human 41BB Ligand Protein

<strong>Human 41BB Ligand Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011520_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> 41BB ligand protein (His tag), CD137L protein, 4 1BB L protein, 4 1BB ligand protein, ILA ligand (TNF related) protein, 4 1BBL protein, TNFSF9 protein, Cd157l protein, Ly63l protein, Cd137l protein, Tumor necrosis factor ligand superfamily member 9 protein, 4-1BBL protein, 4-1BB ligand_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: So T, Ishii N. The TNF-TNFR Family of Co-signal Molecules Adv Exp Med Biol. 2019;1189:53-84._x000D_ 2: Sarnaik AA, Hamid O, Khushalani NI, Lewis KD, Medina T, Kluger HM, Thomas SS, Domingo-Musibay E, Pavlick AC, Whitman ED, Martin-Algarra S, Corrie P, Curti BD, Oláh J, Lutzky J, Weber JS, Larkin JMG, Shi W, Takamura T, Jagasia M, Qin H, Wu X, Chartier C, Graf Finckenstein F, Fardis M, Kirkwood JM, Chesney JA. Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma J Clin Oncol. 2021 Aug 20;39(24):2656-2666._x000D_ 3: Youness RA, Gad AZ, Sanber K, Ahn YJ, Lee GJ, Khallaf E, Hafez HM, Motaal AA, Ahmed N, Gad MZ. Targeting hydrogen sulphide signaling in breast cancer J Adv Res. 2020 Jul 16;27:177-190._x000D_ 4: Cherkassky L, Morello A, Villena-Vargas J, Feng Y, Dimitrov DS, Jones DR, Sadelain M, Adusumilli PS. Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition J Clin Invest. 2016 Aug 1;126(8):3130-44._x000D_ 5: Marin-Acevedo JA, Dholaria B, Soyano AE, Knutson KL, Chumsri S, Lou Y. Next generation of immune checkpoint therapy in cancer: new developments and challenges J Hematol Oncol. 2018 Mar 15;11(1):39._x000D_ 6: Bonnefoy N, Olive D, Vanhove B. [Next generation of anti-immune checkpoints antibodies] Med Sci (Paris). 2019 Dec;35(12):966-974._x000D_ 7: Sun B, Yang D, Dai H, Liu X, Jia R, Cui X, Li W, Cai C, Xu J, Zhao X. Eradication of Hepatocellular Carcinoma by NKG2D-Based CAR-T Cells Cancer Immunol Res. 2019 Nov;7(11):1813-1823._x000D_ 8: Chin SM, Kimberlin CR, Roe-Zurz Z, Zhang P, Xu A, Liao-Chan S, Sen D, Nager AR, Oakdale NS, Brown C, Wang F, Yang Y, Lindquist K, Yeung YA, Salek-Ardakani S, Chaparro-Riggers J. Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab Nat Commun. 2018 Nov 8;9(1):4679._x000D_ 9: Zhao Z, Condomines M, van der Stegen SJC, Perna F, Kloss CC, Gunset G, Plotkin J, Sadelain M. Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells Cancer Cell. 2015 Oct 12;28(4):415-428._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32755564">10: Boroughs AC, Larson RC, Marjanovic ND, Gosik K, Castano AP, Porter CBM, Lorrey SJ, Ashenberg O, Jerby L, Hofree M, Smith-Rosario G, Morris R, Gould J, Riley LS, Berger TR, Riesenfeld SJ, Rozenblatt-Rosen O, Choi BD, Regev A, Maus MV. A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq Mol Ther. 2020 Dec 2;28(12):2577-2592. </a>_x000D_ _x000D_ <strong>Products Related to Human 41BB Ligand Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>