AGDV

AGDV is the γ chain of fibrinogen. AGDV is critical for platelet aggregation[1][2].

Product Specifications

CAS Number

[99896-90-9]

UNSPSC

12352211

Type

Peptides

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/agdv.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(O)=O)=O)=O)[C@H](C)N

Molecular Formula

C14H24N4O7

Molecular Weight

360.36

References & Citations

[1]Lawrence JB, et al. Arginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding. J Clin Invest. 1990 Nov;86 (5) :1715-22. |[2]Plow EF, et al. The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets. Proc Natl Acad Sci U S A. 1985 Dec;82 (23) :8057-61.