SCH 60057

SCH 60057 (Compound 7) is a neurokinin (NK) receptor inhibitor that can be isolated from Acremonium sp., with IC50 values of 6 μM and 12 μM for NK1 and NK2, respectively[1].

Product Specifications

CAS Number

[203061-35-2]

UNSPSC

12352211

Target

Neurokinin Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sch-60057.html

Solubility

10 mM in DMSO

Smiles

OC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CCCC(C)(O)CC/C=C(C)\C

Molecular Formula

C45H84O6

Molecular Weight

721.14

References & Citations

[1]Hegde VR, et al. Neurokinin receptor inhibitors: fermentation, isolation, physico-chemical properties, structure and biological activity. J Antibiot (Tokyo) . 1997 Dec;50 (12) :983-91.