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Prolactin Releasing Peptide (1-31), human (acetate)

Prolactin Releasing Peptide (1-31), human (acetate) is a high affinity GPR10 ligand that causes the release of the prolactin. Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. Prolactin Releasing Peptide (1-31) can be used for the research of the hypothalamo-pituitary axis[1][2].

Product Specifications

UNSPSC

12352209

Target

GnRH Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/prolactin-releasing-peptide-1-31-human-acetate.html

Purity

98.13

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

O=C([C@@H](N)CO)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N)=O)CC4=CC=CC=C4)=O)CCCNC(N)=N)=O)=O)C(C)C)=O)CCC3)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)=O)CCCNC(N)=N)=O)CO)=O)C)=O)CC5=CC=C(O)C=C5)=O)CC6=CNC7=CC=CC=C67)=O)C)=O)CCC2)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC1)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCSC)=O)CO)=O)CC8=CNC=N8)=O)CCCNC(N)=N)=O)CC9=CNC=N9)=O)[C@@H](C)O)=O)CCCNC(N)=N.CC(O)=O

Molecular Formula

C162H256N56O44S

Molecular Weight

3724.17

References & Citations

[1]L J Seal, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141 (5) :1909-12.|[2]Langmead CJ, et al. Characterization of the binding of [ (125) I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Characterization of the binding of [ (125) I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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