R-84760

R-84760 is a selective κ-opioid receptor agonist. R-84760 has antinociceptive effect[1][2].

Product Specifications

CAS Number

[157824-23-2]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/r-84760.html

Smiles

O=C([C@H]1CCC2=C1C=C(Cl)C(Cl)=C2)N3[C@H](CN4CCCC4)CSCC3.Cl

Molecular Formula

C19H25Cl3N2OS

Molecular Weight

435.84

References & Citations

[1]Fujibayashi K, et al. Pharmacological properties of R-84760, a novel kappa-opioid receptor agonist.[J].European Journal of Pharmacology, 1994, 261 (1-2) :133-140.|[2]Fujibayashi K, et al. Profiles of the antinociceptive effect of R-84760, a selective kappa-opioid receptor agonist, in the formalin test in mice. Jpn J Pharmacol. 1995 May;68 (1) :57-63.