5’-O- (4,4-Dimethoxytrityl) -2’-O-methyl inosine
5’-O- (4,4-Dimethoxytrityl) -2’-O-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[128219-84-1]
Product Name Alternative
5'-O- (DIMETHOXYTRITYL) -2'-O-METHYLINOSINE
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-o-4-4-dimethoxytrityl-2-o-methyl-inosine.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@H]4O[C@@H](N5C=NC6=C(N=CN=C65)O)[C@H](OC)[C@@H]4O
Molecular Formula
C32H32N4O7
Molecular Weight
584.62
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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