Rovatirelin
Rovatirelin is an orally active thyrotropin-releasing hormone (TRH) analog. Rovatirelin binds to the human TRH receptor with a Ki value of 702 nM. Rovatirelin can be used to study spinocerebellar degeneration (SCD) [1].
Product Specifications
CAS Number
204386-76-5
Product Name Alternative
S0373
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/rovatirelin.html
Smiles
O=C(N[C@H](C(N1[C@@H](CCC1)C)=O)CCC2=CSC=N2)[C@H]3NC(O[C@H]3C)=O
Molecular Formula
C17H24N4O4S
Molecular Weight
380.46
References & Citations
[1]Ijiro T, et al. Effect of rovatirelin, a novel thyrotropin-releasing hormone analog, on the central noradrenergic system. Eur J Pharmacol. 2015 Aug 15;761:413-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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