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Rovatirelin

Rovatirelin is an orally active thyrotropin-releasing hormone (TRH) analog. Rovatirelin binds to the human TRH receptor with a Ki value of 702 nM. Rovatirelin can be used to study spinocerebellar degeneration (SCD) [1].

Product Specifications

CAS Number

204386-76-5

Product Name Alternative

S0373

UNSPSC

12352005

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/rovatirelin.html

Smiles

O=C(N[C@H](C(N1[C@@H](CCC1)C)=O)CCC2=CSC=N2)[C@H]3NC(O[C@H]3C)=O

Molecular Formula

C17H24N4O4S

Molecular Weight

380.46

References & Citations

[1]Ijiro T, et al. Effect of rovatirelin, a novel thyrotropin-releasing hormone analog, on the central noradrenergic system. Eur J Pharmacol. 2015 Aug 15;761:413-22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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