Purified Anti-Human TCRVβ1 Antibody[BL37.2]
Product Specifications
Background
TCR Vβ1 is a variant of the TCR Vβ chain that is expressed by a subset of αβ+ T cells. Aberrant expression of TCR Vβ chains has been associated with infection and cancer. TCR Vβ1 is reported to be preferably used by autoreactive T cells in a model of autoimmune thyroiditis and diabetes. Skewing of TCR Vβ repertoire to Vβ1 and Vβ9 has also been reported in patients with multiple sclerosis, reactive arthritis, and Kawasaki disease.
Abbreviation
TCRVβ1
UniProt
A0A0B4J1U6
Host
Rat
Reactivity
Human
Immunogen
Recombinant Human TCRVβ1 protein
Target
TRBV; TRBV9
Clonality
Monoclonal
Clone
BL37.2
Conjugation
Unconjugated
Applications
FCM
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Rat IgG1, κ
Available Sizes
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