DL-Norepinephrine-d6 (hydrochloride)

DL-Norepinephrine-d6 (hydrochloride) is the deuterium labeled DL-Norepinephrine hydrochloride. DL-Norepinephrine hydrochloride is a synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine．DL-Norepinephrine hydrochloride is a neurotransmitter targets α1 and β1 adrenoceptors, has an increasing effect on subendocardial oxygen tension[1].

Product Specifications

CAS Number

[1219803-04-9]

UNSPSC

12352005

Hazard Statement

H225, H301+H311+H331, H370

Target

Adrenergic Receptor

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease; Endocrinology

Purity

99.75

Solubility

1 M HCl : 100mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : 25 mg/mL (ultrasonic)

Smiles

NC([2H])([2H])C(C1=C([2H])C(O)=C(C([2H])=C1[2H])O)([2H])O.Cl

Molecular Formula

C8H6D6ClNO3

Molecular Weight

211.68

Precautions

H225, H301+H311+H331, H370

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Matsuda H, et al. Effects of nitroglycerin, adenosine, noradrenaline, and isoproterenol on the myocardial oxygen tension. Jpn Heart J. 1979 Nov;20 (6) :867-79.