Phospho-CrkL (Tyr207) Rabbit PE Conjugate

<strong>Phospho-CrkL (Tyr207) Rabbit PE Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018892_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 33.78 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8℃_x000D_ <strong>Keywords:</strong> Crk-like protein; CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kumar S, Stainer A, Dubrulle J, Simpkins C, Cooper JA. Cas phosphorylation regulates focal adhesion assembly Elife. 2023 Jul 25;12:e90234._x000D_ 2: Estrada A 3rd, Rodriguez AC, Rodriguez G, Grant AH, Ayala-Marin YM, Arrieta AJ, Kirken RA. Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction Sci Rep. 2021 Aug 20;11(1):16951._x000D_ 3: La Rosée P, Holm-Eriksen S, Konig H, Härtel N, Ernst T, Debatin J, Mueller MC, Erben P, Binckebanck A, Wunderle L, Shou Y, Dugan M, Hehlmann R, Ottmann OG, Hochhaus A. Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib Haematologica. 2008 May;93(5):765-9._x000D_ 4: Scopim-Ribeiro R, Machado-Neto JA, Eide CA, Coelho-Silva JL, Fenerich BA, Fernandes JC, Scheucher PS, Savage Stevens SL, de Melo Campos P, Olalla Saad ST, de Carvalho Palma L, de Figueiredo-Pontes LL, Simões BP, Rego EM, Tognon CE, Druker BJ, Traina F. NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia Invest New Drugs. 2021 Jun;39(3):736-746._x000D_ 5: Kong Y, Wu YL, Song Y, Shi MM, Cao XN, Zhao HY, Qin YZ, Lai YY, Jiang H, Jiang Q, Huang XJ. Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL J Transl Med. 2017 Aug 30;15(1):184._x000D_ 6: Lago SG, Tomasik J, van Rees GF, Rustogi N, Vázquez-Bourgon J, Papiol S, Suarez-Pinilla P, Crespo-Facorro B, Bahn S. Peripheral lymphocyte signaling pathway deficiencies predict treatment response in first-onset drug-naïve schizophrenia Brain Behav Immun. 2022 Jul;103:37-49._x000D_ 7: Luo FR, Yang Z, Camuso A, Smykla R, McGlinchey K, Fager K, Flefleh C, Castaneda S, Inigo I, Kan D, Wen ML, Kramer R, Blackwood-Chirchir A, Lee FY. Dasatinib (BMS-354825) pharmacokinetics and pharmacodynamic biomarkers in animal models predict optimal clinical exposure Clin Cancer Res. 2006 Dec 1;12(23):7180-6._x000D_ 8: Dong G, Kalifa R, Nath PR, Gelkop S, Isakov N. TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3ζ chain Biochem Biophys Res Commun. 2017 Jul 1;488(3):541-546._x000D_ 9: Shigeno-Nakazawa Y, Kasai T, Ki S, Kostyanovskaya E, Pawlak J, Yamagishi J, Okimoto N, Taiji M, Okada M, Westbrook J, Satta Y, Kigawa T, Imamoto A. A pre-metazoan origin of the CRK gene family and co-opted signaling network Sci Rep. 2016 Sep 30;6:34349._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27320899">10: Jacob T, Agarwal A, Ramunno-Johnson D, O'Hare T, Gönen M, Tyner JW, Druker BJ, Vu TQ. Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting Sci Rep. 2016 Jun 20;6:28163. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-CrkL (Tyr207) Rabbit PE Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>