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IRS-1 (phospho-Ser318) rabbit pAb

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],

Product Specifications

Background

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

UniProt

P35568

Swiss Prot

P35568

Reactivity

Human; Mouse

Immunogen

Synthesized phosho peptide around human IRS-1 (Ser318)

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

170kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

170kD

Fragment

IgG

Subcellular Location

Nucleus, cytoplasm, cytosol, plasma membrane, insulin receptor complex, caveola, intracellular membrane-bounded organelle

Other Product Names

Insulin receptor substrate 1 (IRS-1)

Gene ID (Human)

3667

Available Sizes

Curated Selection

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