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UT-A1 Antibody (FITC)

Rabbit polyclonal to UT-A1 (FITC) . UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2.) .

Product Specifications

Product Name Alternative

UT-A1, UT-A2, UT1, UT2, UTA, UTA1, UT2_HUMAN, UT2, UTR, SLC14A2, Slc14a2, Solute carrier family 14 member 2, Solute carrier family 14 (urea transporter) member 2, Urea transporter, Urea transporter 2, Urea transporter kidney, HUT2, hUT-A6, FLJ16167, MGC119566, MGC119567, kidney

UniProt

Q62668

Reactivity

Mouse, Rat

Immunogen

Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)

Target

UT-A1

Clonality

Polyclonal

Conjugation

FITC

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purification

Peptide Affinity Purified

Concentration

1 mg/ml

Dilution

WB (1:1000) ; IHC (1:25)

Molecular Weight

97 and 127kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of UT-A1 in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, IHC, WB

NCBI Accession Number

NP_062220

Host or Source

Rabbit

Preservative

640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3

Entrez

54302

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