Dasatinib (monohydrate) (Standard)
Dasatinib (monohydrate) (Standard) is the analytical standard of Dasatinib (monohydrate) . This product is intended for research and analytical applications. Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib monohydrate also induces apoptosis and autophagy.
Product Specifications
CAS Number
863127-77-9
Product Name Alternative
BMS-354825 (monohydrate) (Standard)
UNSPSC
12352005
Target
Apoptosis; Autophagy; Bcr-Abl; Reference Standards; Src
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dasatinib-monohydrate-standard.html
Smiles
O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCO)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl.[H]O[H]
Molecular Formula
C22H28ClN7O3S
Molecular Weight
506.02
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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