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Bassoon Antibody (PerCP)

Rabbit polyclonal to Bassoon (PerCP) . Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors..

Product Specifications

Product Name Alternative

Bassoon, BSN, ZNF231, Zinc finger protein 231, Neuronal double zinc finger protein, KIAA0434

UniProt

Q9UPA5

Reactivity

Human, Mouse, Rat

Immunogen

NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein

Target

Bassoon

Clonality

Polyclonal

Conjugation

PerCP

Field of Research

Disease Biomarkers, Neuroscience

Purification

Protein A Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:400)

Molecular Weight

420kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Bassoon in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

Tested Applications

IHC, WB

NCBI Accession Number

NP_003449.2

Host or Source

Rabbit

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Entrez

8927

Frequently Asked Questions

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