Bassoon Antibody (APC)
Rabbit polyclonal to Bassoon (APC) . Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors..
Product Specifications
Product Name Alternative
Bassoon, BSN, ZNF231, Zinc finger protein 231, Neuronal double zinc finger protein, KIAA0434
UniProt
Q9UPA5
Reactivity
Human, Mouse, Rat
Immunogen
NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
Target
Bassoon
Clonality
Polyclonal
Conjugation
APC
Field of Research
Disease Biomarkers, Neuroscience
Purification
Protein A Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:400)
Molecular Weight
420kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
Tested Applications
IHC, WB
NCBI Accession Number
NP_003449.2
Host or Source
Rabbit
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Entrez
8927
Frequently Asked Questions
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