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Piccolo Antibody (PerCP)

Rabbit polyclonal to Picollo (PerCP) . Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) . Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1..

Product Specifications

Product Name Alternative

Protein piccolo, Aczonin, PCLO, Presynaptic cytomatrix protein, Multidomain presynaptic cytomatrix protein, Piccolo (presynaptic cytomatrix protein), PCLO_HUMAN, ACZ, Pico, Brain-derived HLMN protein, DKFZp779G1236, KIAA0559, Piccolo mouse homolog of Pico

UniProt

Q9Y6V0

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Full length Protein, BC001304.1

Target

Piccolo

Clonality

Polyclonal

Conjugation

PerCP

Field of Research

Disease Biomarkers, Neuroscience

Purification

Protein A Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:400)

Molecular Weight

550kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Piccolo in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

Tested Applications

IHC, WB

NCBI Accession Number

NP_055325.2

Host or Source

Rabbit

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Entrez

27445

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