HSP110 Antibody (HRP)
Rabbit polyclonal to Hsp110 (HRP) . Hsp110 belongs to a family of large stress proteins known as the Hsp110/SSE Family. The proteins in this family are the most distantly known relatives of the well studied Hsp70 family. They share 30-33% amino acid identity, mostly in the conserved ATP-binding domain. Hsp110 cooperates with Hsp70 in protein folding in the eukaryotic cytosol. In mammals, Hsp110 is constitutively expressed, but exhibits particularly high levels in the brain. Both Hsp70 and Hsp110 are elevated after cerebral ischemia. Recent studies demonstrate that the protective effects of Hsp110 deficiency in cerebral ischemia may partly be mediated by an increase in the chaperone activity of Hsp70. Studies also suggest that Hsp110 can be used in heat shock protein-based cancer immunotherapy..
Product Specifications
Product Name Alternative
UniProt
Q92599
Reactivity
Bovine, Fish, Hamster, Human, Monkey, Mouse, Rat, Sheep, Yeast
Immunogen
Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse
Target
HSP110
Clonality
Polyclonal
Conjugation
HRP
Field of Research
Cancer Biology, Cell Biology, Protein Biochemistry, Signal Transduction
Purification
Protein A Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:100)
Molecular Weight
110kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_006635.3
Host or Source
Rabbit
Preservative
73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide, 0.23mM Citrate
Entrez
10808
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