AHA1 Antibody (FITC)

Rabbit polyclonal to Aha1 (FITC) . Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) . Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors..

Product Specifications

Product Name Alternative

AHSA1, AHA1, HSPC322, p38, C14orf3, LOC10598, Activator of Hsp90 ATPase activity 1, Activator of 90 kDa heat shock protein ATPase homolog 1

UniProt

Q8BK64

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Full Length Mouse Aha1 Protein

Target

AHA1

Clonality

Polyclonal

Conjugation

FITC

Field of Research

Cancer Biology, Cell Biology, Protein Biochemistry, Signal Transduction

Purification

Protein A Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:60)

Molecular Weight

38kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μl/ml was sufficient for detection of Aha1 in 10 μg of mixed human cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.