Dehydrozingerone

Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM[1][2][3].

Product Specifications

CAS Number

[1080-12-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Fungal; HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dehydrozingerone.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(/C=C/C1=CC=C(O)C(OC)=C1)=O

Molecular Formula

C11H12O3

Molecular Weight

192.21

Precautions

H302, H315, H319, H335

References & Citations

[1]He K, et al. Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens. J Asian Nat Prod Res. 2016 Jun;18 (6) :528-34.|[2]Kubra IR, et al. Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds. J Food Sci Technol. 2014 Feb;51 (2) :245-55.|[3]Song X, et al. Dehydrozingerone Inspired Discovery of Potential Broad-Spectrum Fungicidal Agents as Ergosterol Biosynthesis Inhibitors. J Agric Food Chem. 2019 Oct 16;67 (41) :11354-11363.