Bay Y5959
Bay Y5959 is a potent calcium channel agonist. Bay Y5959 binds to the DHP receptor in a voltage-dependent manner increases both the mean open time and the mean closed time of the Ca-channel. Bay Y5959 has the potential for the research of congestive heart failure, arrhythmic[1][2].
Product Specifications
CAS Number
146136-94-9
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bay-y5959.html
Smiles
CC(C)OC(C1=C(N)NC(C)=C(C#N)[C@H]1C2=CC=CC3=C2C=C(C4=CC=CC=C4)C=N3)=O
Molecular Formula
C26H24N4O2
Molecular Weight
424.49
References & Citations
[1]Pu J, et al. Effects of Bay Y5959 on Ca2+ currents and intracellular Ca2+ in cells that have survived in the epicardial border of the infarcted canine heart. J Cardiovasc Pharmacol. 1999 Jun;33 (6) :929-37. |[2]Bechem M, et al. A new type of Ca-channel modulation by a novel class of 1,4-dihydropyridines. Life Sci. 1997;60 (2) :107-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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