Bactenecin

Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei[1][2][3].

Product Specifications

CAS Number

[116229-36-8]

Product Name Alternative

Bactenecin, bovine

UNSPSC

12352209

Target

Antibiotic; Bacterial; Fungal

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Bactenecin.html

Solubility

10 mM in DMSO

Smiles

[RLCRIVVIRVCR(Disulfidebridge:Cys3-Cys11)]

Molecular Formula

C63H118N24O13S2

Molecular Weight

1483.89

References & Citations

[1]Gallis B, et al. Antimicrobial activity of synthetic bactenecin. Biotechnol Ther. 1989-1990;1 (4) :335-46.|[2]Radermacher SW, et al. Bactenecin, a leukocytic antimicrobial peptide, is cytotoxic to neuronal and glial cells. J Neurosci Res. 1993 Dec 15;36 (6) :657-62.|[3]Kanjana Madhongsa, et al. Antimicrobial Action of the Cyclic Peptide Bactenecin on Burkholderia Pseudomallei Correlates With Efficient Membrane Permeabilization. PLoS Negl Trop Dis. 2013 Jun 13;7 (6) :e2267.