Ataxin 1 Antibody (FITC)
Mouse monoclonal to Ataxin 1 (FITC) . Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons..
Product Specifications
Product Name Alternative
Ataxin 1, Ataxin-1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein
UniProt
P54254
Reactivity
Human, Mouse, Rat
Immunogen
Target
Ataxin 1
Clonality
Monoclonal
Clone
N65/37 (Formerly sold as S65-37)
Conjugation
FITC
Field of Research
Epigenetics & Chromatin, Neuroscience, Signal Transduction
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
85kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
Tested Applications
ICC, IF, WB
NCBI Accession Number
NP_001186233.1
Host or Source
Mouse
Preservative
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Isotype
IgG1
Entrez
20238
Frequently Asked Questions
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