Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

KCNK3 Antibody (FITC)

Mouse monoclonal to TASK1 Potassium Channel (FITC) . K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels..

Product Specifications

Product Name Alternative

Potassium channel subfamily K member 3, KCNK3, Acid sensitive potassium channel protein TASK 1, Cardiac two pore background K (+) channel, cTBAK 1, K2p3.1, KCNK9, OAT1, rTASK, TASK 1, TBAK1, TWIK related acid sensitive K+ channel, Two pore potassium channel KT3.1, Two pore K (+) channel KT3.1

UniProt

O54912

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1. Mouse: 96% identity (156/161 amino acids identical) . Human: 76% identity (163/161 amino acids identical) . < 30% identity with TASK3.

Target

KCNK3

Clonality

Monoclonal

Clone

N374/48 (Formerly sold as S374-48)

Conjugation

FITC

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100)

Molecular Weight

50kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of TASK1 Potassium Channel in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, IHC, WB

NCBI Accession Number

NP_203694.1

Host or Source

Mouse

Preservative

640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3

Isotype

IgG2b

Entrez

29553

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

SRCAP Rabbit Polyclonal Antibody
orb258584 100 µg

SRCAP Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Rabbit anti-PCIFl Antibody, Affinity Purified
A304-711A-T 10 µg

Rabbit anti-PCIFl Antibody, Affinity Purified

Sign In for Pricing
View Details
EDANS C2 maleimide
617-AAT 25 mg

EDANS C2 maleimide

Sign In for Pricing
View Details
Insulin (INS) ELISA Kit (Goat ELISA Kit
E2806 96 Tests

Insulin (INS) ELISA Kit (Goat ELISA Kit

Sign In for Pricing
View Details
EZR Antibody (FITC)
orb238877-01 50 µg

EZR Antibody (FITC)

Sign In for Pricing
View Details
EZR Antibody (FITC)
orb238877-02 100 µg

EZR Antibody (FITC)

Sign In for Pricing
View Details