QKI Antibody (Biotin)

Mouse monoclonal to QKI (Biotin) . QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients..

Product Specifications

Product Name Alternative

Protein quaking, Hqk, HqkI, KH Domain Containing, RNA Binding (QKI)

UniProt

Q96PU8

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical) . Rat: 99% identity (339/341 amino acids identical) > 90% identity with QKI-6, QKI-7 and QKI-7b.

Target

QKI

Clonality

Monoclonal

Clone

N147/6 (Formerly sold as S147-6)

Conjugation

Biotin

Field of Research

Stem Cell & Developmental Biology

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000)

Molecular Weight

36-38kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Pan-QKI in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.