LGI1 Antibody (PerCP)
Mouse monoclonal to LGI1 (PerCP) . The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form..
Product Specifications
Product Name Alternative
LGI1, Leucine-rich glioma-inactivated protein 1, Epitempin 1, EPT, ETL1, ADLTE, ADPEAF, ADPAEF, IB1099, OTTHUMP00000020121, OTTHUMP00000020122
UniProt
Q9JIA1
Reactivity
Human, Mouse, Rat
Immunogen
Target
LGI1
Clonality
Monoclonal
Clone
N283/7 (Formerly sold as S283-7)
Conjugation
PerCP
Field of Research
Cell Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
60kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
Tested Applications
ICC, IF, IHC, WB
NCBI Accession Number
NP_064674.1
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG2a
Entrez
56839
Frequently Asked Questions
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