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VDAC1 Antibody (APC)

Mouse monoclonal to VDAC1 (APC) . Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis..

Product Specifications

Product Name Alternative

Voltage Dependent Anion Channel 1, Porin, Voltage dependent anion selective channel protein 1, Voltage-dependent anion-selective channel protein 1, hVDAC1, MGC111064, Mitochondrial Porin, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, PORIN-31-HL, VDAC 1, VDAC, VDAC-1

UniProt

P21796

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical) . Rat: 98% identity (279/283 amino acids identical) > 60% identity with VDAC2 and VDAC3.

Target

VDAC1

Clonality

Monoclonal

Clone

N152B/23 (Formerly sold as S152B-23)

Conjugation

APC

Field of Research

Cell Biology

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000)

Molecular Weight

30kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of VDAC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, IHC, WB

NCBI Accession Number

NP_003365.1

Host or Source

Mouse

Preservative

95.46mM Phosphate, 2.48mM MES and 2mM EDTA

Isotype

IgG2a

Entrez

7416

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