LRRK2 Antibody (PerCP)
Mouse monoclonal to LRRK2 (PerCP) . LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features..
Product Specifications
Product Name Alternative
UniProt
Q5S007
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein, amino acids 1-500 (N-terminus) of human LRRK2. 83% identical in mouse and rat. No significant identity with LRRK1.
Target
LRRK2
Clonality
Monoclonal
Clone
N138/6 (Formerly sold as S138-6)
Conjugation
PerCP
Field of Research
Cell Biology
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000)
Molecular Weight
200kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
Tested Applications
ICC, IF, WB
NCBI Accession Number
NP_940980
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG1
Entrez
120892
Frequently Asked Questions
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