GluR1 Antibody (HRP)

Mouse monoclonal to GluA1 (HRP) . Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3) . GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration..

Product Specifications

Product Name Alternative

2900051M01Rik, AI853806, AMPA 1, AMPA selective glutamate receptor 1, GLUH 1, GLUH1, GLUR1, GLURA, Glr-1, Glr1, GluA1, GluR K1, GluR-A, GluR1, GluRA, GluRK1, Glur-1, Glur1, Glutamate receptor 1, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Gria 1, HBGR1, HIPA, MGC13325, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, gluR-

UniProt

P19490

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1

Target

GluR1

Clonality

Monoclonal

Clone

N355/1

Conjugation

HRP

Field of Research

Cell Biology

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100)

Molecular Weight

100kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of GluA1 in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.