LHRH (1-5) (free acid)
LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme[2].
Product Specifications
CAS Number
52434-75-0
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lhrh-1-5-free-acid.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CNC5=CC=CC=C45)=O
Molecular Formula
C34H38N8O9
Molecular Weight
702.71
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]McDermott JR, et al. Mechanism of degradation of LH-RH and neurotensin by synaptosomal peptidases. Peptides. 1983 Jan-Feb;4 (1) :25-30.|[2]Yokosawa H, et al. Degradation of luteinizing hormone-releasing hormone by neuroblastoma cells and their membrane: evidence for the involvement of a thiol protease and angiotensin-converting enzyme. J Neurochem. 1987 Jan;48 (1) :293-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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